3-Aminopiperidine-Based Peptide Analogues as the First Selective Noncovalent Inhibitors of the Bacterial Cysteine Protease IdeS

[Image: see text] A series of eight peptides corresponding to the amino acid sequence of the hinge region of IgG and 17 newly synthesized peptide analogues containing a piperidine moiety as a replacement of a glycine residue were tested as potential inhibitors of the bacterial IgG degrading enzyme o...

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Main Authors: Berggren, Kristina, Vindebro, Reine, Bergström, Claes, Spoerry, Christian, Persson, Helena, Fex, Tomas, Kihlberg, Jan, von Pawel-Rammingen, Ulrich, Luthman, Kristina
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2012
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3310199/
https://ncbi.nlm.nih.gov/pubmed/22369147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201517a
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