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Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis
Modern drug discovery relies on the continual development of synthetic methodology to address the many challenges associated with the design of new pharmaceutical agents(1). One such challenge arises from the enzymatic metabolism of drugs in vivo by cytochrome P450 oxidases, which use single-electro...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3310175/ https://ncbi.nlm.nih.gov/pubmed/22158245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10647 |
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