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Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma
FTY720 is a sphingosine analogue that down regulates expression of sphingosine-1-phosphate receptors and causes apoptosis of multiple tumor cell types, including glioma cells. This study examined the effect of FTY720 on brain tumor stem cells (BTSCs) derived from human glioblastoma (GBM) tissue. FTY...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2012
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309856/ https://ncbi.nlm.nih.gov/pubmed/22351749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos005 |
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