Reduced expression of glucocorticoid-inducible genes GILZ and SGK-1: high IL-6 levels are associated with reduced hippocampal volumes in major depressive disorder

Neuroplasticity may have a core role in the pathophysiology of major depressive disorder (MDD), a concept supported by experimental studies that found that excessive cortisol secretion and/or excessive production of inflammatory cytokines impairs neuronal plasticity and neurogenesis in the hippocamp...

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Detaylı Bibliyografya
Asıl Yazarlar: Frodl, T, Carballedo, A, Hughes, M M, Saleh, K, Fagan, A, Skokauskas, N, McLoughlin, D M, Meaney, J, O'Keane, V, Connor, T J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309536/
https://ncbi.nlm.nih.gov/pubmed/22832853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.14
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