Hypermethylation of serotonin transporter gene in bipolar disorder detected by epigenome analysis of discordant monozygotic twins

Bipolar disorder (BD) is a severe mental disorder characterized by recurrent episodes of mania and depression. Serotonin transporter (HTT) is a target of antidepressants and is one of the strongest candidate molecules of mood disorder, however, genetic study showed equivocal results. Here, we perfor...

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Detalhes bibliográficos
Main Authors: Sugawara, H, Iwamoto, K, Bundo, M, Ueda, J, Miyauchi, T, Komori, A, Kazuno, A, Adati, N, Kusumi, I, Okazaki, Y, Ishigooka, J, Kojima, T, Kato, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309511/
https://ncbi.nlm.nih.gov/pubmed/22832526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2011.26
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