Raphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16

Serotonin reuptake inhibitor (SRI) antidepressants such as fluoxetine (Prozac), promote hippocampal neurogenesis. They also increase the levels of the bcl-2 protein, whose overexpression in transgenic mice enhances adult hippocampal neurogenesis. However, the mechanisms underlying SRI-mediated neuro...

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Detalhes bibliográficos
Main Authors: Launay, J M, Mouillet-Richard, S, Baudry, A, Pietri, M, Kellermann, O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309472/
https://ncbi.nlm.nih.gov/pubmed/22833211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2011.54
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