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Effect of a CCR1 receptor antagonist on systemic trafficking of MSCs and polyethylene particle-associated bone loss

Particle-associated periprosthetic osteolysis remains a major issue in joint replacement. Ongoing bone loss resulting from wear particle-induced inflammation is accompanied by continued attempts at bone repair. Previously we showed that mesenchymal stem cells (MSCs) are recruited systemically to bon...

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Detalhes bibliográficos
Main Authors: Gibon, Emmanuel, Yao, Zhenyu, Rao, Allison J., Zwingenberger, Stefan, Batke, Barbara, Valladares, Roberto, Smith, R. Lane, Biswal, Sandip, Gambhir, Sanjiv S., Goodman, Stuart B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309459/
https://ncbi.nlm.nih.gov/pubmed/22364730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.02.003
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