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Crosslinking of hnRNP proteins to pre-mRNA requires U1 and U2 snRNPs.

Proteins interacting with pre-mRNAs during early stages of spliceosome formation in a HeLa nuclear extract were investigated by photochemical RNA-protein crosslinking. The level of protein crosslinking to a beta-globin pre-mRNA was positively correlated with the presence of an intron. Proteins of 11...

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Publicat a:Nucleic Acids Res
Autors principals: Mayrand, S H, Pederson, T
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1990
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC330938/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2141400/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/18.11.3307
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