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Crosslinking of hnRNP proteins to pre-mRNA requires U1 and U2 snRNPs.

Proteins interacting with pre-mRNAs during early stages of spliceosome formation in a HeLa nuclear extract were investigated by photochemical RNA-protein crosslinking. The level of protein crosslinking to a beta-globin pre-mRNA was positively correlated with the presence of an intron. Proteins of 11...

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Autores principales: Mayrand, S H, Pederson, T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC330938/
https://ncbi.nlm.nih.gov/pubmed/2141400
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