Ebola GP-Specific Monoclonal Antibodies Protect Mice and Guinea Pigs from Lethal Ebola Virus Infection

Ebola virus (EBOV) causes acute hemorrhagic fever in humans and non-human primates with mortality rates up to 90%. So far there are no effective treatments available. This study evaluates the protective efficacy of 8 monoclonal antibodies (MAbs) against Ebola glycoprotein in mice and guinea pigs. Im...

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Bibliografiske detaljer
Main Authors: Qiu, Xiangguo, Fernando, Lisa, Melito, P. Leno, Audet, Jonathan, Feldmann, Heinz, Kobinger, Gary, Alimonti, Judie B., Jones, Steven M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308939/
https://ncbi.nlm.nih.gov/pubmed/22448295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001575
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