Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug

Plasmodium parasites undergo a clinically silent and obligatory developmental phase in the host’s liver cells before they are able to infect erythrocytes and cause malaria symptoms. To overcome the scarcity of compounds targeting the liver stage of malaria, we screened a library of 1037 existing dru...

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Autors principals: da Cruz, Filipa P., Martin, Cécilie, Buchholz, Kathrin, Lafuente-Monasterio, Maria J., Rodrigues, Tiago, Sönnichsen, Birte, Moreira, Rui, Gamo, Francisco-Javier, Marti, Matthias, Mota, Maria M., Hannus, Michael, Prudêncio, Miguel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308910/
https://ncbi.nlm.nih.gov/pubmed/22396598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis184
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