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Reduced Serum IgG Responses to Pneumococcal Antigens in Otitis-Prone Children May Be Due to Poor Memory B-Cell Generation

A low level of serum antibody to antigens expressed by Streptococcus pneumoniae has been proposed to explain the susceptibility of children to recurrent episodes of acute otitis media (hereafter, “otitis-prone children”). By use of enzyme-linked immunospot assays, the percentages of memory B cells t...

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Hlavní autoři: Sharma, Sharad K., Casey, Janet R., Pichichero, Michael E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308907/
https://ncbi.nlm.nih.gov/pubmed/22383675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis179
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