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Reduced Serum IgG Responses to Pneumococcal Antigens in Otitis-Prone Children May Be Due to Poor Memory B-Cell Generation

A low level of serum antibody to antigens expressed by Streptococcus pneumoniae has been proposed to explain the susceptibility of children to recurrent episodes of acute otitis media (hereafter, “otitis-prone children”). By use of enzyme-linked immunospot assays, the percentages of memory B cells t...

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Detalles Bibliográficos
Main Authors: Sharma, Sharad K., Casey, Janet R., Pichichero, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308907/
https://ncbi.nlm.nih.gov/pubmed/22383675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis179
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