Epstein-Barr Viral BNLF2a Protein Hijacks the Tail-anchored Protein Insertion Machinery to Block Antigen Processing by the Transport Complex TAP

Virus-infected cells are eliminated by cytotoxic T lymphocytes, which recognize viral epitopes displayed on major histocompatibility complex class I molecules at the cell surface. Herpesviruses have evolved sophisticated strategies to escape this immune surveillance. During the lytic phase of EBV in...

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Detalhes bibliográficos
Main Authors: Wycisk, Agnes I., Lin, Jiacheng, Loch, Sandra, Hobohm, Kathleen, Funke, Jessica, Wieneke, Ralph, Koch, Joachim, Skach, William R., Mayerhofer, Peter U., Tampé, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308852/
https://ncbi.nlm.nih.gov/pubmed/21984826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.237784
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