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A negative feedback modulator of antigen processing evolved from a frameshift in the cowpox virus genome.

Coevolution of viruses and their hosts represents a dynamic molecular battle between the immune system and viral factors that mediate immune evasion. After the abandonment of smallpox vaccination, cowpox virus infections are an emerging zoonotic health threat, especially for immunocompromised patien...

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Detalhes bibliográficos
Main Authors: Jiacheng Lin, Sabine Eggensperger, Susanne Hank, Agnes I Wycisk, Ralph Wieneke, Peter U Mayerhofer, Robert Tampé
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-12-01
Colecção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC4263761?pdf=render
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