Extremely Conserved ATP- or ADP-dependent Enzymatic System for Nicotinamide Nucleotide Repair

The reduced forms of NAD and NADP, two major nucleotides playing a central role in metabolism, are continuously damaged by enzymatic or heat-dependent hydration. We report the molecular identification of the eukaryotic dehydratase that repairs these nucleotides and show that this enzyme (Carkd in ma...

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Main Authors: Marbaix, Alexandre Y., Noël, Gaëtane, Detroux, Aline M., Vertommen, Didier, Van Schaftingen, Emile, Linster, Carole L.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
主題:
Enzymology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308837/
https://ncbi.nlm.nih.gov/pubmed/21994945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.310847
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