NT-PGC-1α Protein Is Sufficient to Link β(3)-Adrenergic Receptor Activation to Transcriptional and Physiological Components of Adaptive Thermogenesis

PGC-1α is an inducible transcriptional coactivator that regulates cellular energy metabolism and adaptation to environmental and nutritional stimuli. In tissues expressing PGC-1α, alternative splicing produces a truncated protein (NT-PGC-1α) corresponding to the first 267 amino acids of PGC-1α. Brow...

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Main Authors: Chang, Ji Suk, Fernand, Vivian, Zhang, Yubin, Shin, Jeho, Jun, Hee-Jin, Joshi, Yagini, Gettys, Thomas W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308807/
https://ncbi.nlm.nih.gov/pubmed/22282499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.320200
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