Transcriptional Activity of PGC-1α and NT-PGC-1α Is Differentially Regulated by Twist-1 in Brown Fat Metabolism

Brown fat expresses two PGC-1α isoforms (PGC-1α and NT-PGC-1α) and both play a central role in the regulation of cellular energy metabolism and adaptive thermogenesis by interacting with a wide range of transcription factors including PPARγ, PPARα, ERRα, and NRF1. PGC-1α consists of 797 amino acids,...

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Dettagli Bibliografici
Autori principali: Jun, Hee-Jin, Gettys, Thomas W., Chang, Ji Suk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474972/
https://ncbi.nlm.nih.gov/pubmed/23093952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/320454
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