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RAD51 Protein ATP Cap Regulates Nucleoprotein Filament Stability
RAD51 mediates homologous recombination by forming an active DNA nucleoprotein filament (NPF). A conserved aspartate that forms a salt bridge with the ATP γ-phosphate is found at the nucleotide-binding interface between RAD51 subunits of the NPF known as the ATP cap. The salt bridge accounts for the...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308741/ https://ncbi.nlm.nih.gov/pubmed/22275364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.239426 |
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