RAD51 Protein ATP Cap Regulates Nucleoprotein Filament Stability

RAD51 mediates homologous recombination by forming an active DNA nucleoprotein filament (NPF). A conserved aspartate that forms a salt bridge with the ATP γ-phosphate is found at the nucleotide-binding interface between RAD51 subunits of the NPF known as the ATP cap. The salt bridge accounts for the...

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Bibliografische gegevens
Hoofdauteurs: Amunugama, Ravindra, He, Yujiong, Willcox, Smaranda, Forties, Robert A., Shim, Kang-Sup, Bundschuh, Ralf, Luo, Yu, Griffith, Jack, Fishel, Richard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
Onderwerpen:
DNA and Chromosomes
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308741/
https://ncbi.nlm.nih.gov/pubmed/22275364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.239426
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