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Synthesis of Functionalized Dialkyl Ketones From Carboxylic Acid Derivatives and Alkyl Halides

[Image: see text] Unsymmetrical dialkyl ketones can be directly prepared by the nickel-catalyzed reductive coupling of carboxylic acid chlorides or (2-pyridyl)thioesters with alkyl iodides or benzylic chlorides. A wide variety of functional groups are tolerated by this process, including common nitr...

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Hlavní autoři: Wotal, Alexander C., Weix, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308727/
https://ncbi.nlm.nih.gov/pubmed/22360350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol300217x
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