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A stochastic model of kinetochore–microtubule attachment accurately describes fission yeast chromosome segregation

In fission yeast, erroneous attachments of spindle microtubules to kinetochores are frequent in early mitosis. Most are corrected before anaphase onset by a mechanism involving the protein kinase Aurora B, which destabilizes kinetochore microtubules (ktMTs) in the absence of tension between sister c...

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Библиографические подробности
Главные авторы: Gay, Guillaume, Courtheoux, Thibault, Reyes, Céline, Tournier, Sylvie, Gachet, Yannick
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308688/
https://ncbi.nlm.nih.gov/pubmed/22412019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107124
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