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A stochastic model of kinetochore–microtubule attachment accurately describes fission yeast chromosome segregation

In fission yeast, erroneous attachments of spindle microtubules to kinetochores are frequent in early mitosis. Most are corrected before anaphase onset by a mechanism involving the protein kinase Aurora B, which destabilizes kinetochore microtubules (ktMTs) in the absence of tension between sister c...

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Detalhes bibliográficos
Main Authors: Gay, Guillaume, Courtheoux, Thibault, Reyes, Céline, Tournier, Sylvie, Gachet, Yannick
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308688/
https://ncbi.nlm.nih.gov/pubmed/22412019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201107124
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