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DNA methylation of stress-related genes and LINE-1 repetitive elements across the healthy human placenta

OBJECTIVES: DNA methylation is known to play a critical role in regulating development of placental morphology and physiology. The methylation of genes mediated by glucocorticoid hormones may be particularly vulnerable to intrauterine stress in the placenta. However little is known about DNA methyla...

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Autors principals: Non, Amy L., Binder, Alexandra M., Barault, Ludovic, Rancourt, Rebecca C., Kubzansky, Laura D., Michels, Karin B.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308680/
https://ncbi.nlm.nih.gov/pubmed/22222044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2011.12.013
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