Development of a short-term, in vivo mutagenesis assay: the effects of methylation on the recovery of a lambda phage shuttle vector from transgenic mice.

Transgenic mice suitable for the in vivo assay of suspected mutagens at the chromosome level have been constructed by stable integration of a lambda phage shuttle vector. The shuttle vector, which contains a beta-galactosidase (beta-gal) target gene, can be rescued from genomic DNA with in vitro pac...

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Bibliografiske detaljer
Main Authors: Kohler, S W, Provost, G S, Kretz, P L, Dycaico, M J, Sorge, J A, Short, J M
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC330831/
https://ncbi.nlm.nih.gov/pubmed/1693420
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