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Xenopus Nanos1 is required to prevent endoderm gene expression and apoptosis in primordial germ cells
Nanos is expressed in multipotent cells, stem cells and primordial germ cells (PGCs) of organisms as diverse as jellyfish and humans. It functions together with Pumilio to translationally repress targeted mRNAs. Here we show by loss-of-function experiments that Xenopus Nanos1 is required to preserve...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Company of Biologists
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3308181/ https://ncbi.nlm.nih.gov/pubmed/22399685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.079608 |
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