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Xenopus Nanos1 is required to prevent endoderm gene expression and apoptosis in primordial germ cells

Nanos is expressed in multipotent cells, stem cells and primordial germ cells (PGCs) of organisms as diverse as jellyfish and humans. It functions together with Pumilio to translationally repress targeted mRNAs. Here we show by loss-of-function experiments that Xenopus Nanos1 is required to preserve...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lai, Fangfang, Singh, Amar, King, Mary Lou
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Company of Biologists 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308181/
https://ncbi.nlm.nih.gov/pubmed/22399685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.079608
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