Role of major histocompatibility complex class II in the development of autoimmune type 1 diabetes and thyroiditis in rats

Although the MHC class II ‘u' haplotype is strongly associated with type 1 diabetes (T1D) in rats, the role of MHC class II in the development of tissue-specific autoimmune diseases including T1D and autoimmune thyroiditis remains unclear. To clarify this, we produced a congenic strain carrying...

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Bibliographic Details
Main Authors: Yokoi, N, Hidaka, S, Tanabe, S, Ohya, M, Ishima, M, Takagi, Y, Masui, N, Seino, S
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308136/
https://ncbi.nlm.nih.gov/pubmed/21918539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2011.63
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