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The Major Histocompatibility Complex Class II–CD4 Immunologic Synapse in Alcoholic Hepatitis and Autoimmune Liver Pathology: The Role of Aberrant Major Histocompatibility Complex Class II in Hepatocytes

The major histocompatibility complex class II (MHC II)–CD4 immunologic synapse is classically described between the T-cell receptor of CD4-positive lymphocytes and MHC II on antigen-presenting cells. This interaction and others between surrounding costimulatory and checkpoint molecules promote diffe...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Lu, Jiajie G., Ji, Ping, French, Samuel W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943373/
https://ncbi.nlm.nih.gov/pubmed/31669415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.09.019
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