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Improved antiangiogenic and antitumour activity of the combination of the natural flavonoid fisetin and cyclophosphamide in Lewis lung carcinoma-bearing mice

PURPOSE: The natural flavonoid fisetin was recently identified as a lead compound that stabilizes endothelial cell microtubules. In this study we investigated the antiproliferative and antiangiogenic properties of fisetin in vitro and in vivo. METHODS: Fisetin cytotoxicity was evaluated using Lewis...

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Detalhes bibliográficos
Main Authors: Touil, Yasmine S., Seguin, Johanne, Scherman, Daniel, Chabot, Guy G.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3308124/
https://ncbi.nlm.nih.gov/pubmed/21069336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1505-8
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