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Enantioselective Pictet-Spengler Reactions of Isatins for the Synthesis of Spiroindolones

[Image: see text] The condensation cyclization between isatins and 5-methoxy tryptamine catalyzed by chiral phosphoric acids provides spirooxindole tetrahydro-β-carboline products in excellent yields (up to 99%) and enantioselectivity (up to 98:2 er). A comparison of catalysts provides insight for t...

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Detaylı Bibliyografya
Asıl Yazarlar: Badillo, Joseph J., Silva-García, Abel, Shupe, Benjamin H., Fettinger, James C., Franz, Annaliese K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307811/
https://ncbi.nlm.nih.gov/pubmed/22442499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2011.08.071
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