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Constructing and Validating Initial Cα Models from Subnanometer Resolution Density Maps with Pathwalking
A significant number of macromolecular structures solved by electron cryo-microscopy and X-ray crystallography obtain resolutions of 3.5–6Å, at which direct atomistic interpretation is difficult. To address this, we developed pathwalking, a semi-automated protocol to enumerate reasonable Cα models f...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3307788/ https://ncbi.nlm.nih.gov/pubmed/22405004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.01.008 |
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