Constructing and Validating Initial Cα Models from Subnanometer Resolution Density Maps with Pathwalking

A significant number of macromolecular structures solved by electron cryo-microscopy and X-ray crystallography obtain resolutions of 3.5–6Å, at which direct atomistic interpretation is difficult. To address this, we developed pathwalking, a semi-automated protocol to enumerate reasonable Cα models f...

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Bibliographic Details
Main Authors: Baker, Mariah R., Rees, Ian, Ludtke, Steven J., Chiu, Wah, Baker, Matthew L.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307788/
https://ncbi.nlm.nih.gov/pubmed/22405004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.01.008
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