Therapeutic DNA Vaccine Induces Broad T Cell Responses in the Gut and Sustained Protection from Viral Rebound and AIDS in SIV-Infected Rhesus Macaques

Immunotherapies that induce durable immune control of chronic HIV infection may eliminate the need for life-long dependence on drugs. We investigated a DNA vaccine formulated with a novel genetic adjuvant that stimulates immune responses in the blood and gut for the ability to improve therapy in rhe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fuller, Deborah Heydenburg, Rajakumar, Premeela, Che, Jenny W., Narendran, Amithi, Nyaundi, Julia, Michael, Heather, Yager, Eric J., Stagnar, Cristy, Wahlberg, Brendon, Taber, Rachel, Haynes, Joel R., Cook, Fiona C., Ertl, Peter, Tite, John, Amedee, Angela M., Murphey-Corb, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307760/
https://ncbi.nlm.nih.gov/pubmed/22442716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033715
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