Therapeutic DNA Vaccine Induces Broad T Cell Responses in the Gut and Sustained Protection from Viral Rebound and AIDS in SIV-Infected Rhesus Macaques

Immunotherapies that induce durable immune control of chronic HIV infection may eliminate the need for life-long dependence on drugs. We investigated a DNA vaccine formulated with a novel genetic adjuvant that stimulates immune responses in the blood and gut for the ability to improve therapy in rhe...

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Bibliografski detalji
Glavni autori: Fuller, Deborah Heydenburg, Rajakumar, Premeela, Che, Jenny W., Narendran, Amithi, Nyaundi, Julia, Michael, Heather, Yager, Eric J., Stagnar, Cristy, Wahlberg, Brendon, Taber, Rachel, Haynes, Joel R., Cook, Fiona C., Ertl, Peter, Tite, John, Amedee, Angela M., Murphey-Corb, Michael
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307760/
https://ncbi.nlm.nih.gov/pubmed/22442716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033715
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