GM-CSF Increases Mucosal and Systemic Immunogenicity of an H1N1 Influenza DNA Vaccine Administered into the Epidermis of Non-Human Primates

BACKGROUND: The recent H5N1 avian and H1N1 swine-origin influenza virus outbreaks reaffirm that the threat of a world-wide influenza pandemic is both real and ever-present. Vaccination is still considered the best strategy for protection against influenza virus infection but a significant challenge...

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Detalhes bibliográficos
Main Authors: Loudon, Peter T., Yager, Eric J., Lynch, Debbie T., Narendran, Amithi, Stagnar, Cristy, Franchini, Anthony M., Fuller, James T., White, Phil A., Nyuandi, Julia, Wiley, Clayton A., Murphey-Corb, Michael, Fuller, Deborah H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882341/
https://ncbi.nlm.nih.gov/pubmed/20544035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011021
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