A Chemical Analog of Curcumin as an Improved Inhibitor of Amyloid Abeta Oligomerization

Amyloid-like plaques are characteristic lesions defining the neuropathology of Alzheimer's disease (AD). The size and density of these plaques are closely associated with cognitive decline. To combat this disease, the few therapies that are available rely on drugs that increase neurotransmissio...

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Bibliographic Details
Main Authors: Orlando, Robert A., Gonzales, Amanda M., Royer, Robert E., Deck, Lorraine M., Vander Jagt, David L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307704/
https://ncbi.nlm.nih.gov/pubmed/22442659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031869
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