Inherent and Benzo[a]pyrene-Induced Differential Aryl Hydrocarbon Receptor Signaling Greatly Affects Life Span, Atherosclerosis, Cardiac Gene Expression, and Body and Heart Growth in Mice

Little is known of the environmental factors that initiate and promote disease. The aryl hydrocarbon receptor (AHR) is a key regulator of xenobiotic metabolism and plays a major role in gene/environment interactions. The AHR has also been demonstrated to carry out critical functions in development a...

Full description

Saved in:
Bibliographic Details
Main Authors: Kerley-Hamilton, Joanna S., Trask, Heidi W., Ridley, Christian J. A., DuFour, Eric, Lesseur, Corina, Ringelberg, Carol S., Moodie, Karen L., Shipman, Samantha L., Korc, Murray, Gui, Jiang, Shworak, Nicholas W., Tomlinson, Craig R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Genetic Toxicology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307607/
https://ncbi.nlm.nih.gov/pubmed/22228805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs002
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items