Inherent and Benzo[a]pyrene-Induced Differential Aryl Hydrocarbon Receptor Signaling Greatly Affects Life Span, Atherosclerosis, Cardiac Gene Expression, and Body and Heart Growth in Mice

Little is known of the environmental factors that initiate and promote disease. The aryl hydrocarbon receptor (AHR) is a key regulator of xenobiotic metabolism and plays a major role in gene/environment interactions. The AHR has also been demonstrated to carry out critical functions in development a...

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Main Authors: Kerley-Hamilton, Joanna S., Trask, Heidi W., Ridley, Christian J. A., DuFour, Eric, Lesseur, Corina, Ringelberg, Carol S., Moodie, Karen L., Shipman, Samantha L., Korc, Murray, Gui, Jiang, Shworak, Nicholas W., Tomlinson, Craig R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Genetic Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307607/
https://ncbi.nlm.nih.gov/pubmed/22228805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs002
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