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Histone hyperacetylation can induce unfolding of the nucleosome core particle.
A direct correlation exists between the level of histone H4 hyperacetylation induced by sodium butyrate and the extent to which nucleosomes lose their compact shape and become elongated (62.0% of the particles have a length/width ratio over 1.6; overall mean in the length/width ratio = 1.83 +/- 0.48...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1990
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC330759/ https://ncbi.nlm.nih.gov/pubmed/2339060 |
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