Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current

AIMS: Remodelling and regional gradients in expression of connexins (Cx) are thought to contribute to atrial electrical dysfunction and atrial fibrillation. We assessed the effect of interaction between Cx43, Cx40, and Cx45 on atrial cell-to-cell coupling and inward Na current (I(Na)) in engineered...

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Huvudupphovsmän: Desplantez, Thomas, McCain, Megan L., Beauchamp, Philippe, Rigoli, Ghislaine, Rothen-Rutishauser, Barbara, Parker, Kevin Kit, Kleber, Andre G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
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Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307380/
https://ncbi.nlm.nih.gov/pubmed/22287588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs025
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