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Interrogating signaling nodes involved in cellular transformations using kinase activity probes

Protein kinases catalyze protein phosphorylation and thereby control the flow of information through signaling cascades. Currently available methods for concomitant assessment of the enzymatic activities of multiple kinases in complex biological samples rely upon indirect proxies for enzymatic activ...

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Detalhes bibliográficos
Main Authors: Stains, Cliff I., Tedford, Nathan C., Walkup, Traci C., Luković, Elvedin, Goguen, Brenda N., Griffith, Linda G., Lauffenburger, Douglas A., Imperiali, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307342/
https://ncbi.nlm.nih.gov/pubmed/22365604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.11.012
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