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A p38α-Selective Chemosensor for use in Unfractionated Cell Lysates

Recent efforts have identified the p38α Ser/Thr kinase as a potential target for the treatment of inflammatory diseases as well as non-small cell lung carcinoma. Despite the significance of p38α, no direct activity probe compatible with cell lysate analysis exists. Instead, proxies for kinase activa...

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Main Authors: Stains, Cliff I., Luković, Elvedin, Imperiali, Barbara
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025060/
https://ncbi.nlm.nih.gov/pubmed/20845953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100230y
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