γ-Aminobutyric Acid Type A (GABA(A)) Receptor Activation Modulates Tau Phosphorylation

Abnormal phosphorylation and aggregation of the microtubule-associated protein Tau are hallmarks of various neurodegenerative diseases, such as Alzheimer disease. Molecular mechanisms that regulate Tau phosphorylation are complex and currently incompletely understood. We have developed a novel live...

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Autors principals: Nykänen, Niko-Petteri, Kysenius, Kai, Sakha, Prasanna, Tammela, Päivi, Huttunen, Henri J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307276/
https://ncbi.nlm.nih.gov/pubmed/22235112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.309385
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