A functional role for both γ-aminobutyric acid (GABA) transporter-1 and GABA transporter-3 in the modulation of extracellular GABA and GABAergic tonic conductances in the rat hippocampus

Tonic γ-aminobutyric acid (GABA)(A) receptor-mediated signalling controls neuronal network excitability in the hippocampus. Although the extracellular concentration of GABA (e[GABA]) is critical in determining tonic conductances, knowledge on how e[GABA] is regulated by different GABA transporters (...

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Autors principals: Kersanté, Flavie, Rowley, Samuel C S, Pavlov, Ivan, Gutièrrez-Mecinas, María, Semyanov, Alexey, Reul, Johannes M H M, Walker, Matthew C, Linthorst, Astrid C E
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2013
Matèries:
Neuroscience: Cellular/Molecular
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3678035/
https://ncbi.nlm.nih.gov/pubmed/23381899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.246298
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