The Internal Region Leucine-rich Repeat 6 of Decorin Interacts with Low Density Lipoprotein Receptor-related Protein-1, Modulates Transforming Growth Factor (TGF)-β-dependent Signaling, and Inhibits TGF-β-dependent Fibrotic Response in Skeletal Muscles

Decorin is a small proteoglycan, composed of 12 leucine-rich repeats (LRRs) that modulates the activity of transforming growth factor type β (TGF-β) and other growth factors, and thereby influences proliferation and differentiation in a wide array of physiological and pathological processes, such as...

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Hlavní autoři: Cabello-Verrugio, Claudio, Santander, Cristian, Cofré, Catalina, Acuña, Maria José, Melo, Francisco, Brandan, Enrique
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Glycobiology and Extracellular Matrices
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307262/
https://ncbi.nlm.nih.gov/pubmed/22203668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.312488
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