Progressive Multifocal Leukoencephalopathy (PML) Development Is Associated With Mutations in JC Virus Capsid Protein VP1 That Change Its Receptor Specificity

Progressive multifocal leukoencephalopathy (PML), a fatal demyelinating disease caused by JC virus (JCV) infection of oligodendrocytes, may develop in patients with immune disorders following reactivation of chronic benign infection. Mutations of JCV capsid viral protein 1 (VP1), the capsid protein...

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Main Authors: Gorelik, Leonid, Reid, Carl, Testa, Manuela, Brickelmaier, Margot, Bossolasco, Simona, Pazzi, Annamaria, Bestetti, Arabella, Carmillo, Paul, Wilson, Ewa, McAuliffe, Michele, Tonkin, Christopher, Carulli, John P., Lugovskoy, Alexey, Lazzarin, Adriano, Sunyaev, Shamil, Simon, Kenneth, Cinque, Paola
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3307153/
https://ncbi.nlm.nih.gov/pubmed/21628664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir198
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