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Altered Serotonergic Function may Partially Account for Behavioral Endophenotypes in Steroid Sulfatase-deficient Mice

The X-linked gene STS encodes the steroid hormone-modulating enzyme steroid sulfatase. Loss-of-function of STS, and variation within the gene, have been associated with vulnerability to developing attention deficit hyperactivity disorder (ADHD), a neurodevelopmental condition characterized by inatte...

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Detalhes bibliográficos
Main Authors: Trent, Simon, Cassano, Tommaso, Bedse, Gaurav, Ojarikre, Obah A, Humby, Trevor, Davies, William
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306888/
https://ncbi.nlm.nih.gov/pubmed/22189290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2011.314
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