Antilipolytic effect of calcimimetics depends on the allelic variant of calcium-sensing receptor gene polymorphism rs1042636 (Arg990Gly)

Calcium-sensing receptor polymorphism rs1042636 (Arg990Gly) affects the response to the calcimimetic cinacalcet, used to treat hypercalcemia in secondary hyperparathyroidism (sHPT) or parathyroid carcinoma. Carriers of the Arg allelle, show less parathyroid hormone secretion suppression in response...

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Detaylı Bibliyografya
Asıl Yazarlar: Reyes, Marcela, Rothe, Hansjörg M, Mattar, Pamela, Shapiro, Warren B, Cifuentes, Mariana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Short Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306864/
https://ncbi.nlm.nih.gov/pubmed/22166946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.221
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