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A less stressful alternative to oral gavage for pharmacological and toxicological studies in mice
Oral gavage dosing can induce stress and potentially confound experimental measurements, particularly when blood pressure and heart rate are endpoints of interest. Thus, we developed a pill formulation that mice would voluntarily consume and tested the hypothesis that pill dosing would be significan...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3306547/ https://ncbi.nlm.nih.gov/pubmed/22326784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2012.01.025 |
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