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Importance of electrostatic polarizability in calculating cysteine acidity constants and copper(I) binding energy of Bacillus subtilis CopZ

CopZ is a copper chaperone from Bacillus subtilis. It is an important part of Cu(I) trafficking. We have calculated pKa values for the CXXC motif of this protein which is responsible for the Cu(I) binding, and the Cu(I) binding constants. Polarizable and fixed-charges formalisms were employed, and s...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Click, Timothy H., Ponomarev, Sergei Y., Kaminski, George A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306534/
https://ncbi.nlm.nih.gov/pubmed/22370900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.22944
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