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Down-Regulation of Glucose-Regulated Protein (GRP) 78 Potentiates Cytotoxic Effect of Celecoxib in Human Urothelial Carcinoma Cells

Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor that has been reported to elicit anti-proliferative response in various tumors. In this study, we aim to investigate the antitumor effect of celecoxib on urothelial carcinoma (UC) cells and the role endoplasmic reticulum (ER) stress plays i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Kuo-How, Kuo, Kuan-Lin, Chen, Shyh-Chyan, Weng, Te-I, Chuang, Yuan-Ting, Tsai, Yu-Chieh, Pu, Yeong-Shiau, Chiang, Chih-Kang, Liu, Shing-Hwa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3306428/
https://ncbi.nlm.nih.gov/pubmed/22438966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033615
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