Celecoxib-Induced Cytotoxic Effect Is Potentiated by Inhibition of Autophagy in Human Urothelial Carcinoma Cells

Celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, can elicit anti-tumor effects in various malignancies. Here, we sought to clarify the role of autophagy in celecoxib-induced cytotoxicity in human urothelial carcinoma (UC) cells. The results shows celecoxib induced cellular stress response such as en...

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Autors principals: Huang, Kuo-How, Kuo, Kuan-Lin, Ho, I-Lin, Chang, Hong-Chiang, Chuang, Yuan-Ting, Lin, Wei-Chou, Lee, Ping-Yi, Chang, Shih-Chen, Chiang, Chih-Kang, Pu, Yeong-Shiau, Chou, Chien-Tso, Hsu, Chen-Hsun, Liu, Shing-Hwa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857231/
https://ncbi.nlm.nih.gov/pubmed/24349176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082034
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